Swayze, Eric E: search on Z-Library

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1

RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform

Bennett, C. Frank, Swayze, Eric E.

Journal:

Annual Review of Pharmacology

Year:

2010

Language:

english

File:

PDF, 776 KB

english, 2010

2

Pharmacokinetic and Pharmacodynamic Investigations of ION-353382, a Model Antisense Oligonucleotide: Using Alpha-2-Macroglobulin and Murinoglobulin Double-Knockout Mice

Shemesh, Colby S., Yu, Rosie Z., Gaus, Hans J., Seth, Punit P., Swayze, Eric E., Bennett, Frank C., Geary, Richard S., Henry, Scott P., Wang, Yanfeng

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Year:

2016

Language:

english

File:

PDF, 806 KB

english, 2016

3

Pharmacology of Antisense Drugs

Bennett, C. Frank, Baker, Brenda F., Pham, Nguyen, Swayze, Eric, Geary, Richard S.

Journal:

Annual Review of Pharmacology

Year:

2017

Language:

english

File:

PDF, 1.00 MB

english, 2017

4

Efficient Synthesis and Biological Evaluation of 5′-GalNAc Conjugated Antisense Oligonucleotides

Østergaard, Michael E., Yu, Jinghua, Kinberger, Garth A., Wan, W. Brad, Migawa, Michael T., Vasquez, Guillermo, Schmidt, Karsten, Gaus, Hans J., Murray, Heather M., Low, Audrey, Swayze, Eric E., Praka

Journal:

Bioconjugate Chemistry

Year:

2015

Language:

english

File:

PDF, 1.33 MB

english, 2015

5

Fully 2‘-Modified Oligonucleotide Duplexes with Improved in Vitro Potency and Stability Compared to Unmodified Small Interfering RNA

Allerson, Charles R., Sioufi, Namir, Jarres, Russell, Prakash, Thazha P., Naik, Nishant, Berdeja, Andres, Wanders, Lisa, Griffey, Richard H., Swayze, Eric E., Bhat, Balkrishen

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 149 KB

english, 2005

6

HELM Software for Biopolymers

Milton, Jeff, Zhang, Tianhong, Bellamy, Claire, Swayze, Eric, Hart, Christopher, Weisser, Markus, Hecht, Sabrina, Rotstein, Sergio

Journal:

Journal of Chemical Information and Modeling

Year:

2017

Language:

english

File:

PDF, 615 KB

english, 2017

7

Synthetic CRISPR RNA-Cas9–guided genome editing in human cells

Rahdar, Meghdad, McMahon, Moira A., Prakash, Thazha P., Swayze, Eric E., Bennett, C. Frank, Cleveland, Don W.

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.88 MB

english, 2015

8

Synthesis and Biophysical Evaluation of 2′,4′-Constrained 2′ O -Methoxyethyl and 2′,4′-Constrained 2′ O -Ethyl Nucleic Acid Analogues

Seth, Punit P., Vasquez, Guillermo, Allerson, Charles A., Berdeja, Andres, Gaus, Hans, Kinberger, Garth A., Prakash, Thazha P., Migawa, Michael T., Bhat, Balkrishen, Swayze, Eric E.

Journal:

Journal of Organic Chemistry

Year:

2010

Language:

english

File:

PDF, 1.13 MB

english, 2010

9

Single-Stranded siRNAs Activate RNAi in Animals

Lima, Walt F., Prakash, Thazha P., Murray, Heather M., Kinberger, Garth A., Li, Wenyu, Chappell, Alfred E., Li, Cheryl S., Murray, Susan F., Gaus, Hans, Seth, Punit P., Swayze, Eric E., Crooke, Stanle

Journal:

Year:

2012

Language:

english

File:

PDF, 1.64 MB

english, 2012

10

Structure-based design, synthesis and A-site rRNA co-crystal complexes of novel amphiphilic aminoglycoside antibiotics with new binding modes: A synergistic hydrophobic effect against resistant bacteria

Stephen Hanessian, Kandasamy Pachamuthu, Janek Szychowski, Alexandre Giguère, Eric E. Swayze, Michael T. Migawa, Boris François, Jiro Kondo, Eric Westhof

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 461 KB

english, 2010

11

Receptor-Mediated Uptake of Phosphorothioate Antisense Oligonucleotides in Different Cell Types of the Liver

Miller, Colton M., Tanowitz, Michael, Donner, Aaron J., Prakash, Thazha P., Swayze, Eric E., Harris, Edward N., Seth, Punit P.

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Year:

2018

Language:

english

File:

PDF, 746 KB

english, 2018

12

Synthesis and Biological Activity of 5‐Fluorotubercidin

Wang, Xiaojing, Seth, Punit P., Ranken, Ray, Swayze, Eric E., Migawa, Michael T.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2004

Language:

english

File:

PDF, 177 KB

english, 2004

13

Characterization of the interactions of chemically-modified therapeutic nucleic acids with plasma proteins using a fluorescence polarization assay

Gaus, Hans J, Gupta, Ruchi, Chappell, Alfred E, Østergaard, Michael E, Swayze, Eric E, Seth, Punit P

Journal:

Nucleic Acids Research

Year:

2018

File:

PDF, 2.05 MB

2018

14

Disposition and Pharmacokinetics of a GalNAc3-Conjugated Antisense Oligonucleotide Targeting Human Lipoprotein (a) in Monkeys

Yu, Rosie Z., Gunawan, Rudy, Post, Noah, Zanardi, Thomas, Hall, Shannon, Burkey, Jennifer, Kim, Tae-Won, Graham, Mark J., Prakash, Thazha P., Seth, Punit P., Swayze, Eric E., Geary, Richard S., Henry,

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Year:

2016

Language:

english

File:

PDF, 395 KB

english, 2016

15

Design and Synthesis of Paromomycin-Related Heterocycle-Substituted Aminoglycoside Mimetics Based on a Mass Spectrometry RNA-Binding Assay

Yili Ding, Steven A. Hofstadler, Eric E. Swayze, Lisa Risen, Richard H. Griffey

Journal:

Angewandte Chemie International Edition

Year:

2003

Language:

english

File:

PDF, 142 KB

english, 2003

16

Synthesis and biophysical characterization of R-6′-Me-α-l-LNA modified oligonucleotides

Punit P. Seth, Jinghua Yu, Charles R. Allerson, Andres Berdeja, Eric E. Swayze

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 519 KB

english, 2011

17

An Efficient Synthesis of Gougerotin and Related Analogues Using Solid- and Solution-Phase Methodology

Migawa, Michael T., Risen, Lisa M., Griffey, Richard H., Swayze, Eric E.

Journal:

Organic Letters

Year:

2005

Language:

english

File:

PDF, 172 KB

english, 2005

18

An Efficient Synthesis of Mimetics of Neamine for RNA Recognition

Ding, Yili, Hofstadler, Steven A., Swayze, Eric E., Griffey, Richard H.

Journal:

Organic Letters

Year:

2001

Language:

english

File:

PDF, 46 KB

english, 2001

19

Protein production is an early biomarker for RNA ‐targeted therapies

Self, Wade K., Schoch, Kathleen M., Alex, Jacob, Barthélemy, Nicolas, Bollinger, James G., Sato, Chihiro, Cole, Tracy, Kordasiewicz, Holly B., Swayze, Eric, Bateman, Randall J., Miller, Timothy M.

Journal:

Annals of Clinical and Translational Neurology

Year:

2018

File:

PDF, 1.03 MB

2018

20

Antibacterial Aminoglycosides with a Modified Mode of Binding to the Ribosomal-RNA Decoding Site

Boris François, Janek Szychowski, Susanta Sekhar Adhikari, Kandasamy Pachamuthu, Eric E. Swayze, Richard H. Griffey, Michael T. Migawa, Eric Westhof, Stephen Hanessian

Journal:

Angewandte Chemie

Year:

2004

Language:

english

File:

PDF, 237 KB

english, 2004

21

Tobramycin analogues with C-5 aminoalkyl ether chains intended to mimic rings III and IV of paromomycin

Stephen Hanessian, Martin Tremblay, Eric E Swayze

Journal:

Year:

2003

Language:

english

File:

PDF, 1017 KB

english, 2003

22

Secondary amide-based linkers for solid phase organic synthesis

Journal:

Tetrahedron Letters

Year:

1997

Language:

english

File:

PDF, 248 KB

english, 1997

23

Antibacterial activity of quinolone–Macrocycle conjugates

Elizabeth A. Jefferson, Eric E. Swayze, Stephen A. Osgood, Alycia Miyaji, Lisa M. Risen, Lawrence B. Blyn

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 212 KB

english, 2003

24

A Constrained Tricyclic Nucleic Acid Analogue of α- l -LNA: Investigating the Effects of Dual Conformational Restriction on Duplex Thermal Stability

Hanessian, Stephen, Wagger, Jernej, Merner, Bradley L., Giacometti, Robert D., Østergaard, Michael E., Swayze, Eric E., Seth, Punit P.

Journal:

Journal of Organic Chemistry

Year:

2013

Language:

english

File:

PDF, 1.27 MB

english, 2013

25

Reexamination of Neomycin B Degradation: Efficient Preparation of Its CD and D Rings as Protected Glycosyl Donors

Wu, Baogen, Yang, Jun, He, Yun, Swayze, Eric E.

Journal:

Organic Letters

Year:

2002

Language:

english

File:

PDF, 84 KB

english, 2002

26

Synthesis, Improved Antisense Activity and Structural Rationale for the Divergent RNA Affinities of 3′-Fluoro Hexitol Nucleic Acid (FHNA and Ara-FHNA) Modified Oligonucleotides

Egli, Martin, Pallan, Pradeep S., Allerson, Charles R., Prakash, Thazha P., Berdeja, Andres, Yu, Jinghua, Lee, Sam, Watt, Andrew, Gaus, Hans, Bhat, Balkrishen, Swayze, Eric E., Seth, Punit P.

Journal:

Journal of the American Chemical Society

Year:

2011

Language:

english

File:

PDF, 2.96 MB

english, 2011

27

Synthesis, Antiproliferative, and Antiviral Evaluation of Certain Acyclic 6-Substituted Pyrrolo[2,3- D ]-pyrimidine Nucleoside Analogs Related to Sangivamycin and Toyocamycin

Swayze, Eric E., Shannon, William M., Buckheit, Robert W., Wotring, Linda L., Drach, John C., Townsend, Leroy B.

Journal:

Nucleosides and Nucleotides

Year:

1992

Language:

english

File:

PDF, 1.09 MB

english, 1992

28

Antibacterial Aminoglycosides with a Modified Mode of Binding to the Ribosomal-RNA Decoding Site

Boris François, Janek Szychowski, Susanta Sekhar Adhikari, Kandasamy Pachamuthu, Eric E. Swayze, Richard H. Griffey, Michael T. Migawa, Eric Westhof, Stephen Hanessian

Journal:

Angewandte Chemie International Edition

Year:

2004

Language:

english

File:

PDF, 239 KB

english, 2004

29

Probing the functional requirements of the l-haba side-chain of amikacin—synthesis, 16S A-site rRNA binding, and antibacterial activity

Stephen Hanessian, Alexander Kornienko, Eric E Swayze

Journal:

Year:

2003

Language:

english

File:

PDF, 397 KB

english, 2003

30

Characterization of Low-Affinity Complexes between RNA and Small Molecules Using Electrospray Ionization Mass Spectrometry †

Griffey, Richard H., Sannes-Lowery, Kristin A., Drader, Jared J., Mohan, Venkatraman, Swayze, Eric E., Hofstadler, Steven A.

Journal:

Journal of the American Chemical Society

Year:

2000

Language:

english

File:

PDF, 97 KB

english, 2000

31

Structure Activity Relationships of α-L-LNA Modified Phosphorothioate Gapmer Antisense Oligonucleotides in Animals

Seth, Punit P, Jazayeri, Ali, Yu, Jeff, Allerson, Charles R, Bhat, Balkrishen, Swayze, Eric E

Journal:

Molecular Therapy — Nucleic Acids

Year:

2012

Language:

english

File:

PDF, 1.15 MB

english, 2012

32

Solid-phase synthesis of a library of functionalized aminodiol scaffolds

Peter W. Davis, Stephen A. Osgood, Normand Hébert, Kelly G. Sprankle, Eric E. Swayze

Journal:

Biotechnology and Bioengineering

Year:

1999

Language:

english

File:

PDF, 223 KB

english, 1999

33

Antibacterial Activity of Quinolone—Macrocycle Conjugates.

Elizabeth A. Jefferson, Eric E. Swayze, Stephen A. Osgood, Alycia Miyaji, Lisa M. Risen, Lawrence B. Blyn

Journal:

Year:

2003

File:

PDF, 86 KB

2003

34

Efficient Synthesis of Heterocyclic 2-Deoxystreptamine Derivatives as RNA Binding Ligands.

Yili Ding, Steven A. Hofstadler, Eric E. Swayze, Richard H. Griffey

Journal:

Year:

2004

File:

PDF, 159 KB

2004

35

Synthesis and evaluation of novel bacterial rRNA-binding benzimidazoles by mass spectrometry

Yun He, Jun Yang, Baogen Wu, Dale Robinson, Kelly Sprankle, Pei-Pei Kung, Kristin Lowery, V. Mohan, Steve Hofstadler, Eric E. Swayze, Rich Griffey

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 286 KB

english, 2004

36

Improving RNA Interference in Mammalian Cells by 4‘-Thio-Modified Small Interfering RNA (siRNA): Effect on siRNA Activity and Nuclease Stability When Used in Combination with 2‘- O -Alkyl Modifications

Dande, Prasad, Prakash, Thazha P., Sioufi, Namir, Gaus, Hans, Jarres, Russell, Berdeja, Andreas, Swayze, Eric E., Griffey, Richard H., Bhat, Balkrishen

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 270 KB

english, 2006

37

Positional Effect of Chemical Modifications on Short Interference RNA Activity in Mammalian Cells

Prakash, Thazha P., Allerson, Charles R., Dande, Prasad, Vickers, Timothy A., Sioufi, Namir, Jarres, Russell, Baker, Brenda F., Swayze, Eric E., Griffey, Richard H., Bhat, Balkrishen

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 794 KB

english, 2005

38

Structure and nuclease resistance of 2′,4′-constrained 2′-O-methoxyethyl (cMOE) and 2′-O-ethyl (cEt) modified DNAs

Pallan, Pradeep S., Allerson, Charles R., Berdeja, Andres, Seth, Punit P., Swayze, Eric E., Prakash, Thazha P., Egli, Martin

Journal:

Chemical Communications

Year:

2012

Language:

english

File:

PDF, 1.50 MB

english, 2012

39

Synthesis of Neomycin Analogsto Investigate Aminoglycoside-RNA Interactions

Seeberger, Peter H., Baumann, Michael, Zhang, Guangtao, Kanemitsu, Takuya, Swayze, Eric E., Hofstadler, Steven A., Griffey, Richard H.

Journal:

Year:

2003

Language:

english

File:

PDF, 62 KB

english, 2003

40

Fluorinated Nucleotide Modifications Modulate Allele Selectivity of SNP-Targeting Antisense Oligonucleotides

Østergaard, Michael E., Nichols, Josh, Dwight, Timothy A., Lima, Walt, Jung, Michael E., Swayze, Eric E., Seth, Punit P.

Journal:

Molecular Therapy — Nucleic Acids

Year:

2017

Language:

english

File:

PDF, 3.46 MB

english, 2017

41

2-Piperidin-4-yl-benzimidazoles with Broad Spectrum Antibacterial Activities.

Yun He, Baogen Wu, Jun Yang, Dale Robinson, Lisa Risen, Ray Ranken, Lawrence Blyn, Suzie Sheng, Eric E. Swayze

Journal:

Year:

2003

File:

PDF, 79 KB

2003

42

Synthesis and Biological Activity of 5-Fluorotubercidin.

Xiaojing Wang, Punit P. Seth, Ray Ranken, Eric E. Swayze, Migawa Michael T. Migawa Michael T.

Journal:

Year:

2004

File:

PDF, 119 KB

2004

43

Structural requirements for hybridization at the 5′-position are different in α-l-LNA as compared to β-d-LNA

Punit P. Seth, Charles R. Allerson, Michael E. Østergaard, Eric E. Swayze

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 429 KB

english, 2012

44

SAR by MS: A Ligand Based Technique for Drug Lead Discovery Against Structured RNA Targets

Swayze, Eric E., Jefferson, Elizabeth A., Sannes-Lowery, Kristin A., Blyn, Lawrence B., Risen, Lisa M., Arakawa, Satoshi, Osgood, Stephen A., Hofstadler, Steven A., Griffey, Richard H.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 98 KB

english, 2002

45

Co-Administration of an Excipient Oligonucleotide Helps Delineate Pathways of Productive and Nonproductive Uptake of Phosphorothioate Antisense Oligonucleotides in the Liver

Donner, Aaron J., Wancewicz, Edward V., Murray, Heather M., Greenlee, Sarah, Post, Noah, Bell, Melanie, Lima, Walt F., Swayze, Eric E., Seth, Punit P.

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Year:

2017

Language:

english

File:

PDF, 870 KB

english, 2017

46

Corrigendum to “Probing the ribosomal RNA A-site with functionally diverse analogues of paromomycin—synthesis of ring I mimetics”: [Tetrahedron 63 (2007) 827–846]

Stephen Hanessian, Susanta Adhikari, Janek Szychowski, Kandasmy Pachamuthu, Xiaojing Wang, Michael T. Migawa, Richard H. Griffey, Eric E. Swayze

Journal:

Year:

2007

Language:

english

File:

PDF, 98 KB

english, 2007

47

Efficient solution phase synthesis of 2-(N-acyl)-aminobenzimidazoles

Punit P. Seth, Dale E. Robinson, Elizabeth A. Jefferson, Eric E. Swayze

Journal:

Tetrahedron Letters

Year:

2002

Language:

english

File:

PDF, 212 KB

english, 2002

48

2-Piperidin-4-yl-benzimidazoles with broad spectrum antibacterial activities

Yun He, Baogen Wu, Jun Yang, Dale Robinson, Lisa Risen, Ray Ranken, Lawrence Blyn, Suzie Sheng, Eric E Swayze

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 179 KB

english, 2003

49

LRRK2 Antisense Oligonucleotides Ameliorate α-Synuclein Inclusion Formation and in a Parkinson’s disease Mouse Model

Zhao, Hien Tran, John, Neena, Delic, Vedad, Ikeda-Lee, Karli, Kim, Aneeza, Weihofen, Andreas, Swayze, Eric E., Kordasiewicz, Holly B., West, Andrew B., Volpicelli-Daley, Laura

Journal:

Molecular Therapy — Nucleic Acids

Year:

2017

Language:

english

File:

PDF, 3.93 MB

english, 2017

50

An Antisense Oligonucleotide Leads to Suppressed Transcription of Hdac2 and Long-Term Memory Enhancement

Poplawski, Shane G., Garbett, Krassimira A., McMahan, Rebekah L., Kordasiewicz, Holly B., Zhao, Hien, Kennedy, Andrew J., Goleva, Slavina B., Sanders, Teresa H., Motley, S. Timothy, Swayze, Eric E., E

Journal:

Molecular Therapy — Nucleic Acids

Year:

2020

Language:

english

File:

PDF, 2.23 MB

english, 2020

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